I am currently a Group Leader at the Life Sciences Department of the Barcelona Supercomputing Center. My lab, Transcriptomics and Functional Genomics Lab, is interested in understanding how the information encoded in our genome determines gene expression variation across all cell types in our body. We ultimately want to understand how these expression changes in both coding and non-coding genes are associated with specific disease states. Expression datasets are accumulating at high speed and development of new and efficient computational tools to extract relevant biological information of large and interrelated data is crucial. Our lab uses novel computational tools and high-throughput functional assays to tackle these questions.
Previously, I was a postdoc in the Rinn Lab at the Stem Cell and Regenerative Biology Department of Harvard University. During that time, I focused my research on studying in depth the pre- and post-transcriptional regulation of long non-coding RNAs (lncRNAs) to understand the role that lncRNAs play in the regulation of gene expression.
During a first short postdoc in the Guigó Lab (CRG), I focused on the study of the human transcriptome across a wide range of tissues and individuals. In this study, we tried to understand how variation of gene expression and splicing across tissues and individuals can explain human phenotypic variation and can ultimately be linked to disease.
Finally, my PhD was focused on studying the genetic variation of human populations to make inferences on our recent evolutionary history.